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Transcriptional dysregulation of autophagy in the muscle of a mouse model of Duchenne muscular dystrophy

19 May 24 Articles Autophagy dysregulation in DMD ، FoxO and TFEB in Duchenne dystrophy ، mTORC1 pathway and muscle degeneration ، Resveratrol therapy for muscular dystrophy ، Transcriptional regulation of autophagy ، SIRT1 activators and DMD treatment ، Phosphorylation-mediated suppression of FoxOs
Transcriptional dysregulation of autophagy in the muscle of a mouse model of Duchenne muscular dystrophy
This study examines transcriptional dysregulation of autophagy in Duchenne muscular dystrophy, highlighting FoxO and TFEB suppression and resveratrol's therapeutic role.
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Identifying hub genes and dysregulated pathways in Duchenne muscular dystrophy

19 May 24 Articles Hub genes in Duchenne dystrophy ، DMD dysregulated pathways ، Differentially expressed genes in DMD ، Protein-protein interaction network analysis ، Molecular mechanisms of DMD progression ، Gene expression studies in muscular dystrophy ، Therapeutic targets for Duchenne dystrophy
Identifying hub genes and dysregulated pathways in Duchenne muscular dystrophy
This research explores differentially expressed genes (DEGs) and hub genes in Duchenne muscular dystrophy, analyzing their role in disease progression and treatment targets.
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Essential Terminology for Every Reader of Dystrophy Articles

18 May 24 Useful information Muscular dystrophy terminology ، Scientific terms for dystrophy research ، Cohort studies in neuromuscular diseases ، Exome sequencing and genetics ، Understanding dystrophy research ، Basic terms in genetic studies ، Essential glossary for muscular dystrophy
Essential Terminology for Every Reader of Dystrophy Articles
This article provides essential terminology for understanding muscular dystrophy research, covering key scientific terms such as cohort studies and exome sequencing.
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Moving towards successful exon-skipping therapy for Duchenne muscular dystrophy

17 May 24 Articles ، Akinori Nakamura Exon skipping therapy for DMD ، Dystrophin restoration in Duchenne dystrophy ، Antisense oligonucleotide therapy ، Gene therapy for muscular dystrophy ، PMOs and 2’OMeAO for exon skipping ، Multi-exon skipping strategies ، Clinical trials for Duchenne dystrophy treatments
Moving towards successful exon-skipping therapy for Duchenne muscular dystrophy
This review explores exon skipping therapy for Duchenne muscular dystrophy, discussing preclinical and clinical trials, therapeutic challenges, and future developments.
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The Dysferlinopathies Conundrum: Clinical Spectra, Disease Mechanism and Genetic Approaches for Treatments

15 May 24 Articles ، Toshifumi Yokota Dysferlinopathies clinical features ، DYSF gene mutations and muscle weakness ، Muscle membrane repair disorders ، Genetic therapies for dysferlinopathies ، Pharmacological treatments for DYSF-related diseases ، Precision medicine in muscular dystrophies ، Animal models for dysferlinopathy research
The Dysferlinopathies Conundrum: Clinical Spectra, Disease Mechanism and Genetic Approaches for Treatments
This review examines dysferlinopathies, highlighting clinical features, molecular mechanisms, genetic therapies, and the latest research in treatment development.
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Duchenne muscular dystrophy: promising early-stage clinical trials to watch

21 March 24 Articles ، Toshifumi Yokota Duchenne muscular dystrophy clinical trials ، Early-stage DMD treatments ، Exon-skipping therapies for DMD ، Gene therapy for Duchenne dystrophy ، Micro-dystrophin gene therapy ، AON treatments for DMD ، New drugs for Duchenne muscular dystrophy
Duchenne muscular dystrophy: promising early-stage clinical trials to watch
This review highlights early-stage clinical trials for Duchenne muscular dystrophy, covering exon-skipping therapies, gene therapy, and novel treatment strategies.
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Wnt7a is Required for Regeneration of Dystrophic Skeletal Muscle

20 March 24 Articles ، Michael A. Rudnicki ، Ehsan Javandoost Wnt7a and muscle regeneration ، Duchenne muscular dystrophy therapy ، Muscle repair mechanisms in DMD ، Wnt7a injection for muscle healing ، Skeletal muscle recovery factors ، Stem cell activation in muscle repair ، Therapeutic potential of Wnt7a
Wnt7a is Required for Regeneration of Dystrophic Skeletal Muscle
This study examines the role of Wnt7a in muscle regeneration, highlighting its necessity for muscle repair and its potential as a therapy for Duchenne muscular dystrophy.
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Isolation of small extracellular vesicles from regenerating muscle tissue using Tangential Flow Filt

19 March 24 Articles ، Michael A. Rudnicki Extracellular vesicle isolation ، Muscle tissue EV purification ، Tangential Flow Filtration (TFF) for EVs ، Size Exclusion Chromatography (SEC) method ، Wnt7a and extracellular vesicles ، Muscle injury and EV release ، Bioactive vesicles in muscle regeneration
Isolation of small extracellular vesicles from regenerating muscle tissue using Tangential Flow Filt
This study presents an optimized protocol for isolating extracellular vesicles (EVs) from regenerating muscle tissue using TFF and SEC, ensuring purity and efficiency.
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Satellite Cell Heterogeneity in Skeletal Muscle Homeostasis

18 March 24 Articles ، Alessandra Sacco Satellite cell heterogeneity ، Skeletal muscle homeostasis ، Muscle stem cell differentiation ، Self-renewal in satellite cells ، Muscle regeneration mechanisms ، Stem cell fate in muscle repair ، Skeletal muscle stem cell diversity
Satellite Cell Heterogeneity in Skeletal Muscle Homeostasis
This article explores the role of satellite cell heterogeneity in skeletal muscle homeostasis, highlighting its impact on muscle repair, self-renewal, and differentiation.
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