Personal take on this article: The paper explores the vital role of mitochondria in regulating muscle stem cells, particularly satellite cells (SCs), which are crucial for skeletal muscle regeneration. Mitochondria are essential for energy production through oxidative phosphorylation (Oxphos), which supports various metabolic processes and influences SC fate, including their quiescence, activation, self-renewal, and differentiation. This study emphasizes how mitochondrial metabolism adapts to different environmental cues and its …

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