Personal take on this article: This study evaluates the effectiveness of Nusinersen, a drug for treating spinal muscular atrophy (SMA), in adolescents and adults. The researchers conducted a systematic review and meta-analysis of 14 studies involving 539 patients aged 13–72 years, predominantly with SMA Type II or III.  Nusinersen was found to improve or stabilize motor function over 24 months. For the Hammersmith Functional Motor Scale–Expanded (HFMSE), patients showed an …

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