DYSF (Dysferlin): Dysferlin is a protein associated with Miyoshi Myopathy and Limb-Girdle Muscular Dystrophy Type 2B (LGMD2B). Dysferlin plays a crucial role in muscle membrane repair and regeneration. Mutations in the DYSF gene lead to deficiencies in dysferlin, resulting in impaired membrane repair mechanisms and progressive muscle degeneration. Individuals with dysferlinopathies, including Miyoshi Myopathy and LGMD2B, typically experience weakness in the proximal muscles, particularly in the shoulder and pelvic girdle …

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