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Identifying hub genes and dysregulated pathways in Duchenne muscular dystrophy

19 May 24 Articles Hub genes in Duchenne dystrophy ، DMD dysregulated pathways ، Differentially expressed genes in DMD ، Protein-protein interaction network analysis ، Molecular mechanisms of DMD progression ، Gene expression studies in muscular dystrophy ، Therapeutic targets for Duchenne dystrophy
Identifying hub genes and dysregulated pathways in Duchenne muscular dystrophy
This research explores differentially expressed genes (DEGs) and hub genes in Duchenne muscular dystrophy, analyzing their role in disease progression and treatment targets.
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Essential Terminology for Every Reader of Dystrophy Articles

18 May 24 Useful information Muscular dystrophy terminology ، Scientific terms for dystrophy research ، Cohort studies in neuromuscular diseases ، Exome sequencing and genetics ، Understanding dystrophy research ، Basic terms in genetic studies ، Essential glossary for muscular dystrophy
Essential Terminology for Every Reader of Dystrophy Articles
This article provides essential terminology for understanding muscular dystrophy research, covering key scientific terms such as cohort studies and exome sequencing.
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Moving towards successful exon-skipping therapy for Duchenne muscular dystrophy

17 May 24 Articles ، Akinori Nakamura Exon skipping therapy for DMD ، Dystrophin restoration in Duchenne dystrophy ، Antisense oligonucleotide therapy ، Gene therapy for muscular dystrophy ، PMOs and 2’OMeAO for exon skipping ، Multi-exon skipping strategies ، Clinical trials for Duchenne dystrophy treatments
Moving towards successful exon-skipping therapy for Duchenne muscular dystrophy
This review explores exon skipping therapy for Duchenne muscular dystrophy, discussing preclinical and clinical trials, therapeutic challenges, and future developments.
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The Dysferlinopathies Conundrum: Clinical Spectra, Disease Mechanism and Genetic Approaches for Treatments

15 May 24 Articles ، Toshifumi Yokota Dysferlinopathies clinical features ، DYSF gene mutations and muscle weakness ، Muscle membrane repair disorders ، Genetic therapies for dysferlinopathies ، Pharmacological treatments for DYSF-related diseases ، Precision medicine in muscular dystrophies ، Animal models for dysferlinopathy research
The Dysferlinopathies Conundrum: Clinical Spectra, Disease Mechanism and Genetic Approaches for Treatments
This review examines dysferlinopathies, highlighting clinical features, molecular mechanisms, genetic therapies, and the latest research in treatment development.
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Duchenne muscular dystrophy: promising early-stage clinical trials to watch

21 March 24 Articles ، Toshifumi Yokota Duchenne muscular dystrophy clinical trials ، Early-stage DMD treatments ، Exon-skipping therapies for DMD ، Gene therapy for Duchenne dystrophy ، Micro-dystrophin gene therapy ، AON treatments for DMD ، New drugs for Duchenne muscular dystrophy
Duchenne muscular dystrophy: promising early-stage clinical trials to watch
This review highlights early-stage clinical trials for Duchenne muscular dystrophy, covering exon-skipping therapies, gene therapy, and novel treatment strategies.
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Wnt7a is Required for Regeneration of Dystrophic Skeletal Muscle

20 March 24 Articles ، Michael A. Rudnicki ، Ehsan Javandoost Wnt7a and muscle regeneration ، Duchenne muscular dystrophy therapy ، Muscle repair mechanisms in DMD ، Wnt7a injection for muscle healing ، Skeletal muscle recovery factors ، Stem cell activation in muscle repair ، Therapeutic potential of Wnt7a
Wnt7a is Required for Regeneration of Dystrophic Skeletal Muscle
This study examines the role of Wnt7a in muscle regeneration, highlighting its necessity for muscle repair and its potential as a therapy for Duchenne muscular dystrophy.
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Isolation of small extracellular vesicles from regenerating muscle tissue using Tangential Flow Filt

19 March 24 Articles ، Michael A. Rudnicki Extracellular vesicle isolation ، Muscle tissue EV purification ، Tangential Flow Filtration (TFF) for EVs ، Size Exclusion Chromatography (SEC) method ، Wnt7a and extracellular vesicles ، Muscle injury and EV release ، Bioactive vesicles in muscle regeneration
Isolation of small extracellular vesicles from regenerating muscle tissue using Tangential Flow Filt
This study presents an optimized protocol for isolating extracellular vesicles (EVs) from regenerating muscle tissue using TFF and SEC, ensuring purity and efficiency.
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Satellite Cell Heterogeneity in Skeletal Muscle Homeostasis

18 March 24 Articles ، Alessandra Sacco Satellite cell heterogeneity ، Skeletal muscle homeostasis ، Muscle stem cell differentiation ، Self-renewal in satellite cells ، Muscle regeneration mechanisms ، Stem cell fate in muscle repair ، Skeletal muscle stem cell diversity
Satellite Cell Heterogeneity in Skeletal Muscle Homeostasis
This article explores the role of satellite cell heterogeneity in skeletal muscle homeostasis, highlighting its impact on muscle repair, self-renewal, and differentiation.
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Several muscle diseases 5 : DYSF (Dysferlin) , Miyoshi Myopathy

20 February 24 Useful information ، muscle diseases DYSF gene mutation ، Dysferlin deficiency and muscle disease ، Miyoshi myopathy causes and symptoms ، Limb-girdle muscular dystrophy type 2B ، Progressive muscle weakness in dysferlinopathies ، Distal muscle atrophy disorders ، Therapies for Miyoshi myopathy
Several muscle diseases 5 : DYSF (Dysferlin) , Miyoshi Myopathy
This article explores DYSF mutations and Miyoshi Myopathy, detailing the role of dysferlin in muscle membrane repair and how its deficiency leads to muscle degeneration.
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Several muscle diseases 4 : Skeletal Muscle FSHD

19 February 24 Useful information ، muscle diseases Progressive muscle weakness disorders ، FSHD muscular dystrophy ، Facioscapulohumeral muscular dystrophy causes ، DUX4 gene expression in FSHD ، Skeletal muscle dystrophy symptoms ، Autosomal dominant muscle diseases ، FSHD genetic mechanisms
Several muscle diseases 4 : Skeletal Muscle FSHD
This article discusses facioscapulohumeral muscular dystrophy (FSHD), its genetic mechanisms, symptoms, and current research on potential treatments.
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Several muscle diseases 3: LGMD2I, LGMD2B

19 February 24 Useful information ، muscle diseases LGMD2I muscular dystrophy ، LGMD2B causes and symptoms ، Limb-girdle muscular dystrophy types ، DYSF gene mutation and muscle weakness ، FKRP deficiency and glycosylation defects ، Dysferlin role in muscle regeneration ، Genetic muscle diseases with progressive weakness
Several muscle diseases 3: LGMD2I, LGMD2B
This article discusses LGMD2I and LGMD2B, two subtypes of limb-girdle muscular dystrophy, their genetic causes, symptoms, and current management options.
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Several muscle diseases 2: ZNF9 BMD MC-AD DMD TMD

19 February 24 Useful information ، muscle diseases ZNF9 muscular dystrophy ، BMD vs DMD comparison ، Myotonia congenita autosomal dominant (MC-AD) ، Duchenne muscular dystrophy (DMD) symptoms ، Tibial muscular dystrophy (TMD) causes ، Genetic mutations in muscle diseases ، Progressive muscle weakness disorders
Several muscle diseases 2: ZNF9 BMD MC-AD DMD TMD
This article discusses multiple muscle diseases, including ZNF9, BMD, MC-AD, DMD, and TMD, highlighting their genetic causes, symptoms, and disease progression.
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Several muscle diseases 1: DM1 DM2 DMx DM-like DMPK

19 February 24 Useful information ، muscle diseases DM1 myotonic dystrophy ، DM2 vs DM1 symptoms ، DMx muscle disease classification ، DMPK gene mutation ، Myotonia congenita and Thomsen disease ، Genetic causes of myotonic dystrophy ، DM-like conditions ، Muscle stiffness and weakness disorders
Several muscle diseases 1: DM1 DM2 DMx DM-like DMPK
This article explores various muscle diseases, including DM1, DM2, and DMx, detailing their genetic causes, symptoms, and the role of DMPK in myotonic dystrophy.
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Vamorolone improves Becker muscular dystrophy and increases dystrophin protein in bmx model mice

25 June 23 Articles ، Alyson Fiorillo Vamorolone treatment for BMD ، Becker muscular dystrophy therapy ، Dystrophin protein increase ، BMX mouse model research ، Anti-inflammatory drugs for muscular dystrophy ، Inflamma-miRs in muscle diseases ، NF-kB and dystrophin regulation ، DMD and BMD comparative studies
Vamorolone improves Becker muscular dystrophy and increases dystrophin protein in bmx model mice
This study highlights vamorolone’s ability to improve Becker muscular dystrophy by reducing inflammation and increasing dystrophin levels in BMX model mice.
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